Oncology | Andrej Jedinak, PhD Consulting Services

Oncology Expertise Overview

A comprehensive view of our oncology and immuno-oncology capabilities.

Oncology and Immuno-Oncology expertise infographic — click to enlarge

Oncology & Immuno-Oncology expertise map. Click image to view full size.

Our Oncology Expertise

Cancer drug discovery has been transformed by the emergence of immuno-oncology as a paradigm-shifting therapeutic approach. Understanding the complex interplay between tumor cells, the immune system, and the tumor microenvironment is now central to developing the next generation of effective cancer treatments.

Dr. Jedinak brings extensive experience in cancer biology and immuno-oncology, including work on checkpoint inhibitor programs, RNAi-based cancer immunotherapy, and the development of innovative in vitro and in vivo models to assess anti-tumor activity and immune engagement.

From traditional cytotoxic approaches to cutting-edge immunotherapy combinations, we help advance your oncology pipeline with rigorous pharmacology and translational expertise.

Key Oncology Areas

Solid Tumors Hematologic Malignancies Immune Checkpoint Biology Tumor Microenvironment Cancer Immunotherapy RNAi in Oncology

Tumor Types

Melanoma NSCLC Colorectal Cancer Breast Cancer Pancreatic Cancer Lymphoma Leukemia

Key Targets

PD-1 / PD-L1 CTLA-4 TIM-3 / LAG-3 CD47 / SIRPα TIGIT

Oncology Capabilities

Scientific support across the full spectrum of oncology drug discovery and development.

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Tumor Biology

In-depth mechanistic studies of tumor cell biology, oncogenic signaling, and resistance mechanisms using relevant cancer cell models.

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Immuno-Oncology

Immune checkpoint assay development, T cell killing assays, co-culture systems, and tumor-immune cell interaction models.

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TME Analysis

Tumor microenvironment characterization, immune cell profiling, cytokine profiling, and spatial biology approaches for TME-targeting programs.

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In Vivo Oncology Models

Syngeneic, xenograft, and humanized mouse model study design, execution oversight, and tumor immune profiling for anti-tumor efficacy assessment.

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RNAi & Gene Therapy

Specialized expertise in RNAi-based cancer immunotherapy, delivery optimization, and gene expression modulation in immune and tumor cells.

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Translational Strategy

Biomarker identification, patient stratification strategies, and translational pharmacology packages to support clinical program design.