Immunology | Andrej Jedinak, PhD Consulting Services

Immunology Expertise Overview

A comprehensive view of our immunology capabilities and focus areas.

Immunology and Autoimmune Disease expertise infographic — click to enlarge

Immunology & Autoimmune Disease expertise map. Click image to view full size.

Our Immunology Expertise

Immunology represents one of the most productive and complex areas in modern drug discovery. Understanding the intricate interplay between innate and adaptive immunity, cytokine networks, and cellular communication pathways is essential for developing effective treatments for autoimmune and inflammatory diseases.

Dr. Jedinak brings hands-on expertise in immune cell biology, receptor signaling, and the development and validation of disease-relevant pharmacological models. His experience spans both the fundamental mechanisms of immune regulation and the practical challenges of developing modulators of these pathways.

From JAK/STAT inhibitors and biologic DMARDs to emerging cell therapy approaches, we help you navigate the complex immunology landscape with scientific precision.

Key Disease Areas

Rheumatoid Arthritis Inflammatory Bowel Disease Psoriasis Systemic Lupus Erythematosus Multiple Sclerosis

Pathway Expertise

JAK/STAT Signaling NF-κB Pathway TLR Signaling T Cell Activation B Cell Biology Cytokine Networks Complement System Innate Immune Activation

Modalities

Small Molecules Monoclonal Antibodies Bispecific Antibodies RNAi Cell Therapies

Immunology Capabilities

Comprehensive scientific support across all stages of immunology drug discovery.

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Target ID & Validation

Identification and validation of novel immune targets using functional genomics, proteomics, and disease-relevant models.

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Immune Cell Assays

Primary immune cell assay development including T cell, B cell, macrophage, dendritic cell, and NK cell functional studies.

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Ex Vivo Models

Human and animal PBMC systems, whole blood assays, synovial tissue explants, and gut organoid models for disease-relevant profiling.

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In Vivo Disease Models

Arthritis, colitis, psoriasis, and EAE model study design, execution oversight, and translational biomarker integration.

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Biomarker Strategy

Translational biomarker identification and validation for patient stratification and clinical trial design in autoimmune indications.

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Competitive Landscape

Comprehensive analysis of immunology therapeutic landscape, competitor positioning, and white space identification for differentiated programs.

Immunology & Autoimmune Diseases